Pediatric Infectious Disease

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VOLUME 2 , ISSUE 1 ( January-March, 2020 ) > List of Articles

Antimicrobials

Tebipenem: A Novel Oral Carbapenem

Archana Mahalingam

Citation Information : Mahalingam A. Tebipenem: A Novel Oral Carbapenem. Pediatr Inf Dis 2020; 2 (1):25-28.

DOI: 10.5005/jp-journals-10081-1237

License: CC BY-NC 4.0

Published Online: 14-08-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Carbapenems are an important class of drugs very much useful in the therapy of multidrug-resistant gram-negative pathogens. Though these are available for the past 30 years, they can be administered only parenterally, which can reduce the compliance. Tebipenem-pivoxil (TBPM-PI; Orapenem), a prodrug, is the first oral carbapenem. It has been a promising drug in the therapy of drug-resistant respiratory infections and complicated urinary tract infections. It will also be useful in reducing the incidence of central line associated blood stream infections (CLABSI) and improving the rate of treatment completion.


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