Pediatric Infectious Disease

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VOLUME 2 , ISSUE 3 ( July-September, 2020 ) > List of Articles

Immunology Corner

What are Autoinflammatory Diseases?

Keywords : Autoinflammatory diseases, Blau syndrome, Innate immunity, Periodic fevers

Citation Information : What are Autoinflammatory Diseases?. Pediatr Inf Dis 2020; 2 (3):122-124.

DOI: 10.5005/jp-journals-10081-1275

License: CC BY-NC 4.0

Published Online: 25-11-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Autoinflammatory diseases/syndromes are a new group of heterogeneous diseases characterized by “spontaneous onset of inflammation with no evidence of infection, autoimmunity or allergy and occur due to a defect in the innate immune system.” With the advancement of molecular genetics and next-generation sequencing technologies, new diseases are being added to this list every year. In this review, a brief description of a few autoinflammatory diseases would be provided along with a clinical approach. Salient clinical features have been highlighted.


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