Pediatric Infectious Disease

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VOLUME 2 , ISSUE 4 ( October-December, 2020 ) > List of Articles

Original Article

Acute Upper Respiratory Tract Infections in Children and Mode of Delivery

R Kishore Kumar, Nandini Nagar, MV Sowmya

Keywords : Antibiotics, Infants, Lower respiratory tract infection, Mode of delivery, Respiratory tract infection, Retrospective analysis, Single center, Upper respiratory tract infection

Citation Information : Kumar RK, Nagar N, Sowmya M. Acute Upper Respiratory Tract Infections in Children and Mode of Delivery. Pediatr Inf Dis 2020; 2 (4):130-134.

DOI: 10.5005/jp-journals-10081-1259

License: CC BY-NC 4.0

Published Online: 20-02-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background: Studies on prevalence of acute respiratory tract infections (ARTIs) exclusively on the infant population in India, and their association with mode of delivery are lacking. Aims and objectives: To assess the incidence of ARTIs in infants aged <12 months and to delineate its association with the mode of delivery (cesarean and vaginal). We also evaluated the antibiotic use for management of ARTIs in the study population. Study design: This single-center retrospective analysis was carried out in a private hospital (Cloudnine Hospitals) in Karnataka, India, over a period of 12 years from 2007 to July 2019. Participants: The study included 51,850 infants up to 1 year of age who were outpatients or admitted to the hospital with infections. Intervention: In this retrospective study, infection type, mode of delivery, and antibiotic use were recorded. Outcomes: Both upper and lower respiratory tract infections (URTI and LRTI) were observed. Mode of delivery recorded included both cesarean and vaginal, and some infants received antibiotics for ARTI treatment. Results: Higher prevalence of cesarean mode of delivery (71%) was recorded, which was associated with a higher incidence of ARTIs, compared to vaginal delivery (5,648 vs 2,420). Among the ARTI patients, antibiotics were prescribed to 2,635 (21.7%) infants. The commonly prescribed antibiotics were penicillin-type and aminoglycoside antibiotics. Conclusion: The incidence of ARTIs in infants was 23.4%, with URTIs being more prevalent than LRTIs. The prevalence of cesarean delivery was found to be highest and was associated with a higher incidence of ARTIs. Use of antibiotics was observed in 21.7% of infants with ARTIs.


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  1. Chen J, Hu P, Zhou T, et al. Epidemiology and clinical characteristics of acute respiratory tract infections among hospitalized infants and young children in Chengdu, West China, 2009–2014. BMC Pediatr 2018;18(1):216. DOI: 10.1186/s12887-018-1203-y.
  2. Tregoning JS, Schwarze J. Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology. Clin Microbiol Rev 2010;23(1):74–98. DOI: 10.1128/CMR.00032-09.
  3. Anders KL, Nguyen HL, Nguyen NM, et al. Epidemiology and virology of acute respiratory infections during the first year of life: a birth cohort study in Vietnam. Pediatr Infect Dis J 2015;34(4):361–370. DOI: 10.1097/INF.0000000000000643.
  4. Sharma D, Kuppusamy K, Bhoorasamy A. Prevalence of acute respiratory infections (ari) and their determinants in under five children in urban and rural areas of Kancheepuram district, South India. Ann Trop Med Public Health 2013;6:513–518. DOI: 10.4103/1755-6783.133700.
  5. Yousif TK, Khaleq BA. Epidemiology of acute respiratory tract infections (ARI) among children under five years old attending Tikrit General Teaching hospital. Middle East J Fam Med 2006;4(3):1–20.
  6. Paul SP, Wilkinson R, Routley C. Management of respiratory tract infections in children. Nurs: Res Rev (Doverpress) 2014;2014:135–148. DOI: 10.2147/NRR.S43033.
  7. Savitha AK, Gopalakrishnan S. Determinants of acute respiratory infections among under five children in a rural area of Tamil Nadu, India. J Family Med Prim Care 2018;7(6):1268–1273. DOI: 10.4103/jfmpc.jfmpc_131_18.
  8. Merenstein DJ, Gatti ME, Mays DM. The association of mode of delivery and common childhood illnesses. Clinical Pediatrics 2011;50(11):1024–1030. DOI: 10.1177/0009922811410875.
  9. Magnus MC, Håberg SE, Stigum H, et al. Delivery by cesarean section and early childhood respiratory symptoms and disorders: the norwegian mother and child cohort study. Am J Epidemiol 2011;174(11):1275–1285. DOI: 10.1093/aje/kwr242.
  10. Pandey PK, Verma P, Kumar H, et al. Comparative analysis of fecal microflora of healthy full-term Indian infants born with different methods of delivery (vaginal vs cesarean): acinetobacter sp. Prevalence in vaginally born infants. J Biosci 2012;37(6):989–998. DOI: 10.1007/s12038-012-9268-5.
  11. Gondwe T, Betha K, Kusneniwar GN, et al. Mode of delivery and short-term infant health outcomes: a prospective cohort study in a peri-urban Indian population. BMC Pediatr 2018;18(1):346. DOI: 10.1186/s12887-018-1324-3.
  12. Sharma M, Damlin A, Pathak A, et al. Antibiotic prescribing among pediatric in patients with potential infections in two private sector hospitals in central India. PLoS One 2015;10(11):e0142317. DOI: 10.1371/journal.pone.0142317.
  13. Walke SP, Das R, Acharya AS, et al. Incidence, pattern, and severity of acute respiratory infections among infants and toddlers of a peri-urban area of Delhi: a 12 month prospective study. Int Sch Res Notices 2014;2014:165152.
  14. Mathew JL, Patwari AK, Gupta P, et al. Acute respiratory infection and pneumonia in India: a systematic review of literature for advocacy and action: UNICEF-PHFI series on newborn and child health, India. Indian Pediatr 2011;48(1):191–198. DOI: 10.1007/s13312-011-0051-8.
  15. Acharya D, Prasanna KS, Nair S, et al. Acute respiratory infections in children: a community based longitudinal study in South India. Indian J Public Health 2003;47(1):7–13.
  16. Kumar SG, Majumdar A, Kumar V, et al. Prevalence of acute respiratory infection among under-five children in urban and rural areas of Puducherry, India. J Nat Sci Biol Med 2015;6(1):3–6. DOI: 10.4103/0976-9668.149069.
  17. Gupta N, Jain SK, Ratnesh, et al. An evaluation of diarrheal diseases and acute respiratory infections control programmes in a Delhi slum. Indian J Pediatr 2007;74(5):471–476. DOI: 10.1007/s12098-007-0080-4.
  18. Vijayan B, Dhilmon TL, Johnson LR. Prevalence of acute respiratory infections among under five children in a rural area of Kozhikode district, Kerala. Int J Community Med Public Health 2019;6(6):2666–2671. DOI: 10.18203/2394-6040.ijcmph20192341.
  19. Kumar D, Kumar BR. Incidence of acute respiratory tract infections in less than two years children. Int J Contemp Med Res 2017;4(12):6–10.
  20. Islam F, Sarma R, Debroy A, et al. Profiling acute respiratory tract infections in children from Assam. India J Global Infect Dis 2013;5(1):8–14. DOI: 10.4103/0974-777X.107167.
  21. Deb SK. Acute respiratory disease survey in Tripura in case of children below five years of age. J Indian Med Assoc 1998;96(4):111–116.
  22. Prajapati B, Talsania N, Sonaliya KN. A study on prevalence of acute respiratory tract infections (Ari) in under five children in urban and rural communities of Ahmedabad district, Gujarat. Natl J Community Med 2011;2(2):255–259.
  23. Krishnan A, Amarchand R, Gupta V, et al. Epidemiology of acute respiratory infections in children—preliminary results of a cohort in a rural north Indian community. BMC Infect Dis 2015;15:462. DOI: 10.1186/s12879-015-1188-1.
  24. Ramachandrappa A, Jain L. Elective cesarean section: its impact on neonatal respiratory outcome. Clin Perinatol 2008;35(2):373–393. DOI: 10.1016/j.clp.2008.03.006.
  25. Darabi B, Rahmati S, HafeziAhmadi MR, et al. The association between caesarean section and childhood asthma: an updated systematic review and meta-analysis. Allergy Asthma Clin Immunol 2019;15:62. DOI: 10.1186/s13223-019-0367-9.
  26. Kristensen K, Fisker N, Haerskjold A, et al. Caesarean section and hospitalization for respiratory syncytial virus infection: a population-based study. Pediatr Infect Dis J 2015;34(2):145–148. DOI: 10.1097/INF.0000000000000552.
  27. Moore HC, de Klerk N, Holt P, et al. Hospitalisation for bronchiolitis in infants is more common after elective caesarean delivery. Arch Dis Child 2012;97(5):410–414. DOI: 10.1136/archdischild-2011-300607.
  28. Thavagnanam S, Fleming J, Bromley A, et al. A meta-analysis of the association between caesarean section and childhood asthma. Clin Exp Allergy 2008;38(4):629–633. DOI: 10.1111/j.1365-2222.2007.02780.x.
  29. Moore HC, Hall GL, de Klerk N. Infant respiratory infections and later respiratory hospitalisation in childhood. Eur Respir J 2015;46(5):1334–1341. DOI: 10.1183/13993003.00587-2015.
  30. Lavin T, Franklin P, Preen DB. Association between caesarean delivery and childhood asthma in India and Vietnam. Paediatr Perinat Epidemiol 2017;31(1):47–54. DOI: 10.1111/ppe.12324.
  31. Schaad UB, Esposito S, Razi CH. Diagnosis and management of recurrent respiratory tract infections in children: a practical guide. Arch Pediatr Infect Dis 2016;4(1):e31039.
  32. Ministry of Health and Family Welfare, Government of India. Management of Management of common Respiratory Infections in Children in India. July 2016. Available at: http://clinicalestablishments.gov.in/WriteReadData/4671.pdf Accessed on: 03 January, 2020.
  33. Rogawski ET, Platts-Mills JA, Seidman JC, et al. Use of antibiotics in children younger than two years in eight countries: a prospective cohort study. Bull World Health Organ 2017;95(1):49–61. DOI: 10.2471/BLT.16.176123.
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