The neurological manifestations of coronavirus disease-2019 (COVID-19) infection in children is not well documented. We hereby report a case of tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus and multiple arterial infarcts. The overlapping clinical presentation posed a diagnostic and therapeutic challenge.
Mao L, Jin H, Wang M, et al. Neurological manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol 2020;77(6):683–690. DOI: 101001/jamaneurol20201127.
Lu X, Zhang L, Du H, et al. SARS-CoV-2 infection in children. N Engl J Med 2020;382(17):1663–1665. DOI: 10.1056/NEJMc2005073.
Essajee F, Solomons R, Goussard P, et al. Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis. BMJ Case Rep CP 2020;13(9):e238597. DOI: 10.1136/bcr-2020-238597.
McAbee GN, Brosgol Y, Pavlakis S, et al. Encephalitis associated with COVID-19 infection in an 11-year-old child. Pediatr Neurol 2020;109:94. DOI: 10.1016/j.pediatrneurol.2020.04.013.
Kinikar A, Kulkarni R, Rajput U, et al. Acute encephalopathy in a child with coronavirus disease-2019 infection. Pediatr Inf Dis 2020;2(2):62–63.
Pradhan S. Hydrocephalus and vasculitis delay therapeutic responses in tuberculous meningitis: the neurologist's perspective. Neurol India 2016;64(5):860–861. DOI: 10.4103/0028-3886.190293.