Background: Fungal paranasal sinusitis most commonly observed infection in immunocompromised hosts or patients with uncontrolled diabetes mellitus. In immunocompromised hosts like patients with leukemia on chemotherapy, it can become life-threatening infection.
Case description: We present a case report of a 6-year-old male child who presented as a case of febrile neutropenia. Diagnosis of invasive paranasal sinusitis by Aspergillus fumigatus was made and treatment with voriconazole commenced. But due to underlying refractory leukemia the child succumbed.
Conclusion: A high index of suspicion of invasive aspergillosis (IA) should be kept in the mind with careful clinical examination should be done in acute lymphoblastic leukemia (ALL) patients with prolonged duration of neutropenia.
Clinical significance: Importance of early diagnosis of fungal sinusitis and early initiation of treatment in leukemic patients.
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