Pediatric Infectious Disease

Register      Login

VOLUME 4 , ISSUE 3 ( July-September, 2022 ) > List of Articles

CASE REPORT

Multisystem Inflammatory Syndrome in a Child with Post-acute COVID-19 Infection Presenting as Kawasaki-like Illness

Venkat Reddy, Aditya V Kabra, Sudharshan Raj Chitgupiker

Keywords : COVID-19, IV Immunoglobulin, Kawasaki mimic, Multisystem inflammatory syndrome in childhood

Citation Information : Reddy V, Kabra AV, Chitgupiker SR. Multisystem Inflammatory Syndrome in a Child with Post-acute COVID-19 Infection Presenting as Kawasaki-like Illness. Pediatr Inf Dis 2022; 4 (3):109-110.

DOI: 10.5005/jp-journals-10081-1287

License: CC BY-NC 4.0

Published Online: 31-08-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Amidst increasing concerns of children presenting with multisystem inflammatory syndrome (MIS) simulating Kawasaki disease, we report a child with MIS-C presented with abdominal pain and fever. A 9-year-old child presented with acute febrile illness, abdominal pain, and later had skin rash with mild bulbar conjunctivitis, oral mucosal erythema, and posterior pharyngeal congestion. Investigations showed high inflammatory markers, leukopenia with neutrophil predominance with high CRP (205 mg/L), ESR (89), D-dimer, and ferritin. Reverse transcriptase polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was negative, but antibodies for SARS-CoV-2 was strongly reactive. During hospital stay, he developed arthralgia and tachypnea requiring oxygen. He was treated with oxygen, IV immunoglobulins, aspirin, steroids, and low-molecular-weight (LMW) heparin. Child has responded well, with fever and rash subsiding in 24 hours and no further complications.


PDF Share
  1. Who, Multisystem Inflammatory Syndrome In Children And Adolescents With Covid-19. Available From: Https://Www.who.int/Publications/I/Item/Multisystem-Inflammatory-Syndrome-In-Children-And-Adolescents-With-Covid-19. 2020;(May):1–3.
  2. CDC, Health Department-Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C) in the United States MIS-C Cases by Jurisdiction Race and Ethnicity of Reported MIS-C Cases. Available from: https://www.cdc.gov/mis-c/cases/index.html. 2020.
  3. Swann OV, Holden KA, Turtle L, et al. Clinical characteristics of children and young people admitted to hospital with COVID-19 in United Kingdom: prospective multicentre observational cohort study. Br J Med 2020;370(m3249):1–2. http://www.bmj.com/. DOI: 10.1136/bmj.m3249
  4. Feldstein LR, Rose EB, Horwitz SM, et al. Multisystem inflammatory syndrome in U.S. children and adolescents. N Eng J Med 2020;383(4):343.
  5. Royal College of Paediatrics and Child Health Guidance, “Paediatric multisystem inflammatory syndrome temporally associated with COVID-19,” 2020, https://www.rcpch.ac.uk/sites/default/files/2020-05/COVID-19-Paediatric-multisystem-%20inflammatory%20syndrome-20200501.pdf.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.