Pediatric Infectious Disease

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VOLUME 3 , ISSUE 1 ( January-March, 2021 ) > List of Articles

Antimicrobials

Use of Antifungals Other Than Amphotericin B for Invasive Fungal Infections in Neonates and Children

Jeeson C Unni

Keywords : Antifungal agents, Caspofungin, Children, Fluconazole, Itraconazole, Neonate

Citation Information : Unni JC. Use of Antifungals Other Than Amphotericin B for Invasive Fungal Infections in Neonates and Children. Pediatr Inf Dis 2021; 3 (1):38-42.

DOI: 10.5005/jp-journals-10081-1256

License: CC BY-NC 4.0

Published Online: 00-03-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Antifungal therapy for neonates, children, and adolescents, especially in those with primary or secondary immunodeficiencies having invasive fungal infections, is possible today due to the advent of newer antifungals. Studies of antifungals in the pediatric age-group are limited to those for cutaneous fungal infections. Although there are a few studies on the pharmacokinetics and safety, these drugs are used off-label, and most dosage recommendations are extrapolated from the adult data. A review of the use of antifungals other than amphotericin B for treatment of invasive fungal infections in pediatrics is the focus of this article.


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