Pediatric Infectious Disease

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VOLUME 4 , ISSUE 1 ( January-March, 2022 ) > List of Articles

Antimicrobial

Is Amoxicillin Effective in Treatment of Acute Otitis Media in Routine Outpatient Practice?

Sudhir V Sane, Jayashree R Balip, Shwetha Vernekar

Keywords : Acute otitis, Amoxicillin, Antibiotics, Effectivity

Citation Information : Sane SV, Balip JR, Vernekar S. Is Amoxicillin Effective in Treatment of Acute Otitis Media in Routine Outpatient Practice?. Pediatr Inf Dis 2022; 4 (1):13-15.

DOI: 10.5005/jp-journals-10081-1311

License: CC BY-NC 4.0

Published Online: 08-02-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim and objective: To evaluate the effectiveness of low-dose amoxicillin in otitis media. Materials and methods: All children presenting to our outpatient clinic with signs and symptoms suggestive of otitis media and need of antibiotics according to AAP criteria were enrolled. Intervention: A 10-day course of oral amoxicillin at 40 mg/kg/day in three divided doses. Main outcome: Symptomatic relief after 48 hours and normal tympanic membrane at the end of therapy. Results: There were 201 cases. One hundred and sixty-one out of these completed a 10-day course of amoxicillin. One hundred and forty-six (90.68%. 95% CI 86.17–95.18%) responded to amoxicillin. On follow-up of these 67.44% had normal tympanic membrane whereas 33.56% had persistent middle ear fluid. Conclusion: Amoxicillin remains the first-line therapy in the treatment of acute otitis media (AOM) in children.


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