There are very few guidelines available that focus on recommended diluents for intravenous (IV) administration of the various antimicrobial used in pediatric practices. This article attempts to detail ideal diluents for commonly used antimicrobials; the amount of diluent to be added for IV administration; analyze various methods of IV administration; explains how diluents could be reduced while treating children in whom fluid restriction improves outcome; and suggests methods of reducing wastage of costly antimicrobials and thereby economizes therapy of sick children.
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