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VOLUME 4 , ISSUE 4 ( October-December, 2022 ) > List of Articles
Neha Singh, Sagar Bhattad
Keywords : Autoimmunity, Immune deficiency, Immune dysregulation
Citation Information : Singh N, Bhattad S. Autoimmunity and Inborn Errors of Immunity: Two Faces of the Same Coin!. Pediatr Inf Dis 2022; 4 (4):153-155.
License: CC BY-NC 4.0
Published Online: 31-12-2022
Copyright Statement: Copyright © 2022; The Author(s).
Autoimmune disorders are a heterogeneous group of disorders characterized by immune dysregulation and are associated with a loss of tolerance to self-antigens. Autoimmunity in patients with inborn errors of immunity (IEI) has always been a puzzling phenomenon! Autoimmunity may be the first clinical presentation or sequel in patients with IEI. In this paper, we discuss the mechanisms of autoimmunity in IEI and present a few clinical cases highlighting the need to consider an IEI in patients presenting with autoimmunity and infections, polyautoimmunity, and polyendocrinopathy.