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VOLUME 5 , ISSUE 1 ( January-March, 2023 ) > List of Articles
H Chandrashekar, Basavaraja Gangasamudra Veerappa, Nijaguna Nangundappa, Prahalad Kumar Appadorai, Sanjay K Shivappa
Keywords : BCG adenitis, BCG vaccine, Primary immunodeficiency, Severe combined immunodeficiency (SCID)
Citation Information : Chandrashekar H, Veerappa BG, Nangundappa N, Appadorai PK, Shivappa SK. Disseminated BCG Infection in Immunocompromised Child: A Case Report. Pediatr Inf Dis 2023; 5 (1):25-26.
License: CC BY-NC 4.0
Published Online: 15-04-2023
Copyright Statement: Copyright © 2023; The Author(s).
Bacillus Calmette-Guérin (BCG) is a live bacterial vaccine of Mycobacterium bovis to prevent tuberculosis (TB). It is given at birth or as early as possible according to the national immunization schedule. Usually, BCG is well tolerated. Severe adverse events following BCG vaccinations include local abscess, ulceration, and suppurative abscess. Disseminated BCGosis is the most devastating adverse event with a high fatality rate. It is seen most commonly in infants with primary immunodeficiencies or infants born with human immunodeficiency virus (HIV) infection. Here we present a 7-month female child who presented initially with BCG adenitis and was later diagnosed with disseminated mycobacterial infection; hence investigated, and the diagnosis was confirmed as severe combined immunodeficiency (SCID).