COVID-19 and Tuberculosis Coinfection: An Observational Study
Sushant Satish Mane, Jyothi Janardhanan, Manas Pustake, Gazi Israil Khan, Nisha Yadav, Akshay Wanvat, Mohammed Kashif Ali, Rajratna Chopade
Coinfection, COVID-19, Tuberculosis
Citation Information :
Mane SS, Janardhanan J, Pustake M, Khan GI, Yadav N, Wanvat A, Ali MK, Chopade R. COVID-19 and Tuberculosis Coinfection: An Observational Study. Pediatr Inf Dis 2023; 5 (2):45-48.
Background: COVID-19 is a highly infectious disease with a wide range of symptoms, from asymptomatic to acute respiratory distress syndrome that may even lead to death. Tuberculosis also is one of the deadliest respiratory infections. There is still a lack of literature about coinfection of these diseases in both adults and children.
Materials and methods: This retrospective study was performed in a tertiary care hospital in Mumbai, in which children with TB and those without a TB diagnosis were enrolled. All patients were tested for COVID-19 infection. Variables significantly associated with COVID-19 positivity, in children with TB were assessed and analyzed. Treatment protocols for COVID-19 were compared in children with TB and those without.
Results: No variable was significantly associated with COVID-19 positivity in children with TB. The mean duration of hospital stay for COVID-19 was not significantly different between the TB and non-TB groups. COVID-19 treatment did not differ in children with TB compared to those without. In both groups, children who succumbed to COVID-19 were the ones who required invasive ventilation along with steroids and had significant lesions on their chest radiology. Symptomatic treatment was all that was needed for the vast majority of the milder cases.
Conclusion: The management of COVID-19 is unrelated to the status of TB infection. We must fight new pandemics while ensuring that those in need of attention from ongoing illnesses like TB are provided with uninterrupted health care. We should not forget to suspect and manage TB appropriately (in the case of coinfection), as it is still one of the leading infectious causes of death worldwide.
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