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VOLUME 6 , ISSUE 2 ( April-June, 2024 ) > List of Articles


C-Tb Skin Test: A Step Toward Tuberculosis Eradication

Harshini T Reddy, Bhaskar Shenoy

Keywords : C-Tb, Culture filtrate protein 10, Early secretory antigenic target 6, Interferon γ-release assay, QuantiFERON gold in tube test, Tuberculin skin test

Citation Information : Reddy HT, Shenoy B. C-Tb Skin Test: A Step Toward Tuberculosis Eradication. Pediatr Inf Dis 2024; 6 (2):55-56.

DOI: 10.5005/jp-journals-10081-1423

License: CC BY-NC 4.0

Published Online: 15-05-2024

Copyright Statement:  Copyright © 2024; The Author(s).


C-Tb is a novel diagnostic test for latent tuberculosis (TB) infection. It is a skin test based on the principle of tuberculin skin test containing early secreted antigenic target 6 (ESAT-6) and culture filtrate protein 10 (CFP-10). It is important to understand newer diagnostics for TB in order to move towards the goal of eradication of TB. This test helps in early diagnosis and treatment of latent TB infection in high-risk individuals who can develop active TB. It is field-friendly and cost-effective, which comes with the ease of tuberculin skin test and the accuracy of interferon γ-release assay (IGRA).

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